SUPPLEMENT

Lung Cancer Over 17 Years of Aspen Lung Conferences

York E. Miller and Robert L. Keith
Chest 125: 79S. [Full Text] [PDF]  

Environmental Causes of Lung Cancer: What Do We Know in 2003?

Jonathan M. Samet
Chest 125: 80S-83S. [Abstract] [Full Text] [PDF]  

Increased Urinary 8-Isoprostaglandin F₂ Is Associated With Lower Plasma Selenium Levels and Lower Vegetable and Fruit Intake in an Asbestos-Exposed Cohort at Risk for Lung Cancer

E. Brigitte Gottschall, Pam Wolfe, Albert D. Haegele, Zongjian Zhu, Cecile S. Rose, Tricia Sells, and Henry J. Thompson
Chest 125: 83S. [Full Text] [PDF]  

p53: At the Crossroads of Molecular Carcinogenesis and Molecular Epidemiology

Lorne J. Hofseth, Ana I. Robles, Qin Yang, Xin W. Wang, S. Perwez Hussain, and Curtis Harris
Chest 125: 83S-85S. [Full Text] [PDF]  

Development of Lung Tumors in Mutant p53-Expressing Mice After Inhalation Exposure to Asbestos

Gilbert F. Morris, Amy R. Notwick, Odile David, Cesar Fermin, Arnold R. Brody, and Mitchell Friedman
Chest 125: 85S-86S. [Full Text] [PDF]  

Genetic Predisposition to Lung Cancer

Ann G. Schwartz
Chest 125: 86S-89S. [Full Text] [PDF]  

Lung Cancer Risk in Relatives of Early-Onset Lung Cancer Cases

Michele L. Cote, Angela J. Spindler, and Ann G. Schwartz
Chest 125: 89S-90S. [Full Text] [PDF]  

Premalignant Evolution of Lung Cancer: Gilles F. Filley Lecture

Wilbur A. Franklin
Chest 125: 90S-94S. [Full Text] [PDF]  

Preinvasive Bronchial Lesions: Surveillance or Intervention?

Anindo K. Banerjee, Pamela H. Rabbitts, and P. Jeremy George
Chest 125: 95S-96S. [Full Text] [PDF]  

Serial Analysis of Gene Expression Profiles of Developmental Stages in Non-small Cell Lung Carcinoma

Calum MacAulay, Kim Lonergan, Bryan Chi, Scott Zuyderduyn, Jaquie Shein, Ming Tsao, Jean LeRiche, Steven Jones, Marco Marra, Stephen Lam, and Wan L. Lam
Chest 125: 97S. [Full Text] [PDF]  

Molecular Targets for Cancer Therapy and Prevention

Adi F. Gazdar, Kuniharu Miyajima, Jyotsna Reddy, Ubaradka G. Sathyanarayana, Hisayuki Shigematsu, Makoto Suzuki, Takao Takahashi, and Narayan Shivapurkar
Chest 125: 97S-101S. [Abstract] [Full Text] [PDF]  

Tobacco Carcinogen-Induced Cellular Transformation Increases Akt Activation In Vitro and In Vivo

Kip A. West, Ilona R. Linnoila, John Brognard, Steven Belinsky, Curtis Harris, and Phillip A. Dennis
Chest 125: 101S-102S. [Full Text] [PDF]  

Role of P63 Amplification and Overexpression in Lung Cancer Development

Pierre P. Massion, Peter M. Taflan, S.M. Jamshedur Rahman, Pinar Yildiz, Yu Shyr, David P. Carbone, and Adriana L. Gonzalez
Chest 125: 102S. [Full Text] [PDF]  

Evaluation of H37, a Candidate 3p21.3 Tumor Suppressor Gene, as a Therapeutic and Diagnostic Marker in Lung Cancer

Juliana J. Oh, Michael C. Fishbein, Baher Boctor, Cynthia A. Jimenez, Robert Lopez, and Dennis J. Slamon
Chest 125: 102S-103S. [Full Text] [PDF]  

Molecular Classification of Lung Cancer: A Cross-Platform Comparison of Gene Expression Data Sets

Giovanni Parmigiani, Elizabeth Garrett, Ramaswamy Anbazhagan, and Edward Gabrielson
Chest 125: 103S. [Full Text] [PDF]  

Class Prediction of Lung Nodule Gene Expression Profiles

Kristin L. Walter, Alain C. Borczuk, Ligun Q. Wang, Adel M. Assaad, J.H.M. Austin, Gregory D. Pearson, Maria C. Shiau, and Charles A. Powell
Chest 125: 104S. [Full Text] [PDF]  

Construction and Optimization of Chromosome Arm-Specific Comparative Genomic Hybridization Arrays for Identifying Genetic Alterations in Preinvasive Lung Cancers

Cathie Garnis, Bradley Coe, Laura-Jane Henderson, Adrian Ishkanian, Spencer Watson, Marco Marra, John Minna, Stephen Lam, Calum MacAulay, and Wan Lam
Chest 125: 104S-105S. [Full Text] [PDF]  

Efficient Identification and Use of Tumor-Associated Antibodies as Markers of Non-small Cell Lung Cancer

Li Zhong, Xuejun Peng, Giovana E. Hidalgo, Dennis E. Doherty, Arnold S. Stromberg, and Edward A. Hirschowitz
Chest 125: 105S-106S. [Full Text] [PDF]  

Caveolin-1 Is Down-Regulated in Human Lung Carcinoma and Acts as a Candidate Tumor Suppressor Gene

Martin M. Bélanger, Élise Roussel, and Jacques Couet
Chest 125: 106S. [Full Text] [PDF]  

Retrovirus-Induced Lung Cancer: Mechanisms of Transformation of Alveolar Type II Epithelial Cells

James C. DeMartini, Judy A. Platt, Amanda Evans, Dennis R. Voelker, and Thomas E. Allen
Chest 125: 106S-107S. [Full Text] [PDF]  

Selective Suppression of Dendritic Cell Functions by Cigarette Smoke Extract

Robert Vassallo and Lieping Chen
Chest 125: 107S. [Full Text] [PDF]  

Buccal-Lung Comparison of Quantitative Expression of Carcinogen and Oxidant Metabolism Genes in Human Subjects

R.J. Jain, S. Varma, G.J. Hurteau, and Simon D. Spivack
Chest 125: 107S-108S. [Full Text] [PDF]  

Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia as a Precursor to Pulmonary Neuroendocrine Tumors

John R. Gosney
Chest 125: 108S. [Full Text] [PDF]  

Serum Levels of Surfactant Protein D Are Increased in Mice With Lung Tumors

F. Zhang, W. Pao, S. Umphress, S. Jakowlew, A.M. Meyer, L.D. Dwyer-Nield, K. Takeda, E.W. Gelfand, J. Fisher, A.M. Malkinson, and Robert J. Mason
Chest 125: 109S. [Full Text] [PDF]  

High Prevalence of Endobronchial Malignancy in High-Risk Patients With Moderate Dysplasia in Sputum

Timothy C. Kennedy, Wilbur A. Franklin, Sheila A. Prindiville, Robert Cook, Edward C. Dempsey, Robert L. Keith, Fred R. Hirsch, Thomas A. Merrick, Kenneth R. Shroyer, Thomas L. Petty, Tim Byers, Paul A. Bunn, Jr, and York E. Miller
Chest 125: 109S. [Full Text] [PDF]  

Regulated Gap Junction-Cytoskeletal Associations in Rat Alveolar Epithelial Cells

Yihe Guo, Cara Martinez-Williams, and D. Eugene Rannels
Chest 125: 110S. [Full Text] [PDF]  

Improvement and Application of Fluorescence Inter-Simple Sequence Repeat Polymerase Chain Reaction for the Study of Subclonal Growths in Lung Epithelial Cell Populations

Tao Lu and Walter N. Hittelman
Chest 125: 110S-111S. [Full Text] [PDF]  

Sprouty 2 Gene in Mouse Lung Tumorigenesis

George Minowada and York E. Miller
Chest 125: 111S. [Full Text] [PDF]  

Gene Expression Patterns, Prognostic and Diagnostic Markers, and Lung Cancer Biology

Naftali Kaminski and Meir Krupsky
Chest 125: 111S-115S. [Full Text] [PDF]  

Impact of Cigarette Smoke on the Normal Airway Transcriptome

Avrum Spira, Frank Schembri, Jennifer Beane, Vishal Shah, Gang Liu, and Jerome S. Brody
Chest 125: 115S. [Full Text] [PDF]  

Non-small Cell Lung Cancer Molecular Profiles Are Associated With Lung Development

Alain C. Borczuk, Adel M. Assaad, Liqun Q. Wang, Kristin L. Walter, and Charles A. Powell
Chest 125: 115S-116S. [Full Text] [PDF]  

Elevated Hepatocyte Growth Factor Level Correlates With Poor Outcome in Early-Stage and Late-Stage Adenocarcinoma of the Lung

Jill M. Siegfried, James D. Luketich, Laura P. Stabile, Neil Christie, and Stephanie R. Land
Chest 125: 116S-119S. [Full Text] [PDF]  

Epigenetics in Lung Cancer: Focus on Progression and Early Lesions

James G. Herman
Chest 125: 119S-122S. [Full Text] [PDF]  

-Catenin Expression Is Reduced or Absent in a Subset of Human Non-small Cell Lung Cancers, and Its Re-expression Inhibits Cell Growth

Robert A. Winn and Lynn E. Heasley
Chest 125: 122S-123S. [Full Text] [PDF]  

Human Lung Cancer Chemoprevention Strategies: Parker B. Francis Lecture

Gilbert S. Omenn
Chest 125: 123S-127S. [Abstract] [Full Text] [PDF]  

Airway Antioxidants and Oxidative Stress as Predictors of Sputum Atypia and Airflow Obstruction

Russell P. Bowler, Beth Duda, Kieu O. Vu, Tim Byers, Wilbur Franklin, Edward D. Chan, and York E. Miller
Chest 125: 127S-128S. [Full Text] [PDF]  

Chemoprevention of Tobacco Smoke-Induced Lung Cancer: What Animal Studies Tell Us

Hanspeter Witschi, Imelda Espiritu, Dale Uyeminami, Kent E. Pinkerton, and Otto G. Raabe
Chest 125: 128S. [Full Text] [PDF]  

Mechanisms of Chemoprevention

Zbigniew Walaszek, Margaret Hanausek, and Thomas J. Slaga
Chest 125: 128S-133S. [Full Text] [PDF]  

The Chemokine Receptor, CXCR2, Mediates the Tumorigenic Effects of ELR+ CXC Chemokines

Michael P. Keane, Marie D. Burdick, Ying Ying Xue, Marin Lutz, John A. Belperio, and Robert M. Strieter
Chest 125: 133S. [Full Text] [PDF]  

Ligands of Peroxisome Proliferator-Activated Receptor Inhibit Lung Cancer Cell Growth and Induce Apoptosis by Stimulation of P21 Expression

Shouwei Han, Neil Sidell, Paul B. Fisher, and Jesse Roman
Chest 125: 134S. [Full Text] [PDF]  

Cyclooxygenase-2 in Lung Carcinogenesis and Chemoprevention: Roger S. Mitchell Lecture

Joanne R. Brown and Raymond N. DuBois
Chest 125: 134S-140S. [Full Text] [PDF]  

Cyclooxygenase-2–Dependent Expression of Survivin in Non-small Cell Lung Cancer

Kostyantyn Krysan, Mariam Dohadwala, Jie Luo, Ying Lin, Li Zhu, Nathalie Heuze-Vourc’h, Lee Goodglick, Farrukh Merchant, David Seligson, Mehis Pold, Robert Strieter, Sherven Sharma, and Steven Dubinett
Chest 125: 140S. [Full Text] [PDF]  

Prostacyclin in Human Non-small Cell Lung Cancers

Patrick Nana-Sinkam, Heiko Golpon, Robert L. Keith, Ryan J. Oyer, Sylk Sotto-Santiago, Mark D. Moore, Wilbur Franklin, Raphael A. Nemenoff, and Mark W. Geraci
Chest 125: 141S. [Full Text] [PDF]  

Role of Protein Kinase B-Dependent Signaling in Lung Tumorigenesis

Jonathan M. Kurie
Chest 125: 141S-144S. [Abstract] [Full Text] [PDF]  

Chemoprevention of Lung Cancer in Transgenic Mice

Ronald A. Lubet, Zhongqiu Zhang, Yian Wang, and Ming You
Chest 125: 144S-147S. [Full Text] [PDF]  

New Lung Cancer Drugs From Bradykinin Antagonists

John M. Stewart, Lajos Gera, Daniel C. Chan, Eunice J. York, Laimute T. Stewart, Vitalija Simkeviciene, and Barbara Helfrich
Chest 125: 148S. [Full Text] [PDF]  

A Multicenter Study Comparing Autofluorescence Bronchoscopy to White Light Bronchoscopy Using a Non-Laser Light Stimulation System

John F. Beamis, Jr, Armin Ernst, Michael Simoff, Rex Yung, and Praveen Mathur
Chest 125: 148S-149S. [Full Text] [PDF]  

Modulation of Biomarkers During Chemoprevention of Mouse Lung Tumorigenesis by D-glucarate

Margaret Hanausek, Zbigniew Walaszek, Janusz Szemraj, Robert Zoltaszek, and Thomas J. Slaga
Chest 125: 149S. [Full Text] [PDF]  

Mechanisms of Lung Cancer Chemoprevention by D-Glucarate

Zbigniew Walaszek, Margaret Hanausek, Maciej Narog, Peter C. Raich, and Thomas J. Slaga
Chest 125: 149S-150S. [Full Text] [PDF]  

Role of Parathyroid Hormone-Related Protein in Lung Cancer Cell Survival

Randolph H. Hastings, Flavio Araiza, Douglas W. Burton, and Leonard J. Deftos
Chest 125: 150S. [Full Text] [PDF]  

Potential Role for Activated Leukocyte Cell Adhesion Molecule and Neural Cadherin in Metastasis to the Lung Microcirculation

Judy King, Solomon Ofori-Acquah, Troy Stevens, and Abu-Bakr Al-Mehdi
Chest 125: 150S-151S. [Full Text] [PDF]  

Sputum Dysplasia, Related to Bacterial Load, Oxidative Stress, and Airway Inflammation in COPD

Philip E. Silkoff, Ashley Busacker, John Trudeau, Mary Jackson, and Wilbur Franklin
Chest 125: 151S. [Full Text] [PDF]  

Phospho-Akt Overexpression in Non-small Cell Lung Cancer Confers Significant Stage-Independent Survival Disadvantage

Odile David, Helena LeBeau, Arnold R. Brody, Mitchell Friedman, and James Jett
Chest 125: 152S. [Full Text] [PDF]  

Lung Cancer Screening Using Low-Dose High-Resolution CT Scanning in a High-Risk Workforce: 3,500 Nuclear Fuel Workers in Three US States

Albert Miller, Steven Markowitz, Amy Manowitz, and Jeffrey A. Miller
Chest 125: 152S-153S. [Full Text] [PDF]  

Activation of the Akt/Nuclear Factor-B Signaling Axis in Developing Lung Neoplasia

Jay W. Tichelaar, Yu Zhang, Jean C. leRiche, Stephen Lam, and Marshall W. Anderson
Chest 125: 153S. [Full Text] [PDF]  

New Targets for Detection and Treatment of Small Cell Lung Cancer

Nina Pedersen, Mikkel W. Pedersen, Thomas T. Poulsen, Shila Mortensen, Susanne B. Sørensen, Klaus Rieneck, Lone F. Bovin, and Hans Skovgaard Poulsen
Chest 125: 154S. [Full Text] [PDF]  

Evidence That Inflammation Encourages Pulmonary Adenocarcinoma Formation in Mice: Clinical Implications

Alvin M. Malkinson
Chest 125: 154S-155S. [Full Text] [PDF]  

Use of Standardized Reverse Transcription-Polymerase Chain Reaction and the Standardized Expression Measurement Center in Multi-institutional Trials To Develop Meaningful Lung Cancer Classification Based on Molecular Genetic Criteria

James C. Willey, Charles R. Knight, Erin L. Crawford, Dan E. Olson, Jeffrey Hammersly, Youngsook Yoon, and Imran Sharief
Chest 125: 155S-156S. [Full Text] [PDF]  

The SDF-1/CXCL 12/CXCR4 Biological Axis in Non-small Cell Lung Cancer Metastases

John A. Belperio, Roderick J. Phillips, Marie D. Burdick, Marin Lutz, Michael Keane, and Robert Strieter
Chest 125: 156S. [Full Text] [PDF]  

A Pilot Evaluation of Micrometastases for the Prediction of Outcome in Lung Cancer

Austin B. Thompson, Anne Kessinger, and J. Graham Sharp
Chest 125: 156S-157S. [Full Text] [PDF]  

Effects of Budesonide on Overall 5-Methylcytosine Levels and Specific Methylation and Messenger RNA Expression of the Insulin-Like Growth Factor II Gene in Mouse Lung Tumors

Ronald Lubet, Lianhui Tao, Wei Wang, Paula Kramer, and Michael Perreira
Chest 125: 157S. [Full Text] [PDF]  

Improved Diagnostic Sensitivity for Lung Cancer Using an Automated Quantitative Cytology System and Uridine 5'-Triphosphate-Induced Sputum Specimens

Fred L. Johnson, Bojana Turic, Roger Kemp, Branko Palcic, Robert Sussman, Kirk G. Voelker, and Emory Robinette
Chest 125: 157S-158S. [Full Text] [PDF]  

Screening for Lung Cancer: Current Status and Future Directions: Thomas A. Neff Lecture

James R. Jett and David E. Midthun
Chest 125: 158S-162S. [Abstract] [Full Text] [PDF]  

Lung Cancer Detection in Asymptomatic Patients With Airflow Obstruction

Joel J. Bechtel, W Kelley, T Coons, G Klein, D Slagel, and Thomas L. Petty
Chest 125: 163S. [Full Text] [PDF]  

Bimodality Lung Cancer Screening in High-Risk Patients: A Preliminary Report

Gregory Loewen, Mary Reid, DongFeng Tan, Donald Klippenstein, Enriqueta Nava, Raj Natarajan, and Martin Mahoney
Chest 125: 163S-164S. [Full Text] [PDF]  

Detection of Melanoma Antigen-A Expression in Sputum and Bronchial Lavage Fluid of Patients With Lung Cancer

Ingo Mecklenburg, Diana F. Stratakis, Rudolf M. Huber, Karl Häussinger, Alicia Morresi-Hauf, Gert Riethmüller, and Peter Kufer
Chest 125: 164S-166S. [Full Text] [PDF]  

Experience With Surgical Intervention for Screening-Detected Lung Cancer

Masahiro Tsuboi, Norihiko Ikeda, and Harubumi Kato
Chest 125: 167S. [Full Text] [PDF]  

Lung Cancer: Early Events, Early Interventions: Conference Summary for the 46th Annual Thomas L. Petty Aspen Lung Conference

David P. Carbone
Chest 125: 167S-172S. [Full Text] [PDF]  

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