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Contents: Volume 114/Number 1 Supplement/July, 1998 [Index by Author]
"Thomas L. Petty 40th Annual Aspen Lung Conference: Biology [amp ] Pathobiology of the Lung Circulation"
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Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF)

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ARTICLES

Introduction: Biology & Pathobiology of the Lung Circulation: Framing the Issues
Norbert F. Voelkel Chest Jul 1998: 1S. [PDF]

Histopathology of Pulmonary Hypertension
Rubin M. Tuder, Sang-Do Lee, and Carlyne C. Cool Chest Jul 1998: 1S–6S. [PDF]

Formation of the Pulmonary Vasculature: Elastic Fiber Proteins as Markers of Cellular Differentiation and Vascular Development
J. M. W. Hausladen, E. C. Davis, R. A. Pierce, and Robert P. Mecham Chest Jul 1998: 6S. [PDF]

Altered Vascular Development in Preterm Lambs With Chronic Lung Injury
Kurt H. Albertine, A. N. MacRitchie, B. J. Young, S-C Cho, L. K. Kullama, D. P. Carlton, and R. D. Bland Chest Jul 1998: 6S–7S. [PDF]

Hemodynamics Modulate Pulmonary Artery Response to Injury
K Okada, Y. Tanaka, M. Bernstein, W. Zhang, and M. D. Botney Chest Jul 1998: 7S–8S. [PDF]

Blood Flow Distribution in the Lung
Robb W. Glenny Chest Jul 1998: 8S–16S. [PDF]

Robust Design of the Lung: Fractal Patterns and Capillary Independence
Wiltz W. Wagner, Jr., T. M. Todoran, N. Tanabe, T. M. Wagner, R. W. Glenny, and R. G. Presson, Jr. Chest Jul 1998: 16S–17S. [PDF]

Hemodynamic Effects of Dipyridamole and Inhaled Nitric Oxide in Pediatric Patients With Pulmonary Hypertension
D. Dunbar Ivy, J. W. Ziegler, John P. Kinsella, J. W. Wiggins, and Steven H. Abman Chest Jul 1998: 17S. [PDF]

Pulmonary Vasoconstriction, Oxygen Sensing, and the Role of Ion Channels: Thomas A. Neff Lecture
E. Kenneth Weir, Helen L. Reeve, Douglas A. Peterson, Evangelos D. Michelakis, Daniel P. Nelson, and Stephen L. Archer Chest Jul 1998: 17S–22S. [PDF]

Oxidant Stress Stimulates Na/K Pump Activity in Bovine Pulmonary Arterial Endothelial Cells
Sharon Rounds, Michael Cutaia, Amos Charles, Joseph Meharg, Doloretta Dawicki, Eben Oldmixon, and Charles Kuhn Chest Jul 1998: 22S–24S. [PDF]

Hypoxia Enhances Proliferation and Generation of IP₃ in Pulmonary Artery Fibroblasts But Not in Those From the Mesenteric Circulation
Andrew J. Peacock, P. Scott, R. Plevin, R. Wadsworth, and D. Welsh Chest Jul 1998: 24S. [PDF]

Mechanical Load Enhances the Stimulatory Effect of PDGF on Pulmonary Artery Fibroblast Procollagen Synthesis
Jill E. Bishop, R. Butt, K. Dawes, and G. Laurent Chest Jul 1998: 25S. [PDF]

Hypoxic Responses of Vascular Cells
Stella Kourembanas, Toshisuke Morita, Helen Christou, Yuxiang Liu, Hideo Koike, Dara Brodsky, Victoria Arthur, and S. Alex Mitsial Chest Jul 1998: 25S–28S. [PDF]

Hypoxia Stimulates Proliferation of a Unique Cell Population Isolated From the Bovine Vascular Media
Maria G. Frid, Almaz A. Aldashev, Gary F. Cabirac, Edward C. Dempsey, and Kurt R. Stenmark Chest Jul 1998: 28S–29S. [PDF]

Hypoxic Growth of Bovine Pulmonary Artery Smooth Muscle Cells: Dependence on Synergy, Heterogeneity, and Injury-Induced Phenotypic Change
Edward C. Dempsey, Mita Das, Maria G. Frid, Yongjian Xu, and Kurt R. Stenmark Chest Jul 1998: 29S–30S. [PDF]

Low or Absent Peptidase Expression in Plexiform Lesions of Primary Pulmonary Hypertension
Andrea J. Cohen, Carlyne Cool, Samita Gorg, Laura B. Gilman, Rubin M. Tuder, York E. Miller, and Norbert F. Voelkel Chest Jul 1998: 30S–31S. [PDF]

Myosin Heavy Chain (SMMHC) SM-B Isoform Is Differentially Expressed in Developing and Adult Smooth Muscle Tissues of the Rat
Robert B. Low and Sheryl L. White Chest Jul 1998: 31S–33S. [PDF]

Hypoxia Upregulates Inducible (Type II) Nitric Oxide Synthase in an HIF-1 Dependent Manner in Rat Pulmonary Microvascular But Not Aortic Smooth Muscle Cells
Lisa A. Palmer and Roger A. Johns Chest Jul 1998: 33S–34S. [PDF]

Cultured Rat Main Pulmonary Artery Smooth Muscle Cells Exhibit at Least Two Polyamine Transport Phenotypes That Differ Morphologically and in Response to Hypoxia
Pavel Babal and Mark N. Gillespie Chest Jul 1998: 34S–35S. [PDF]

Remodeling of the Na/H Antiport and the Cytoskeleton of Human Pulmonary Artery Endothelial Cells: Response to an Oxygen Deficit
Michael Cutaia, N. Parks, Sharon I.S. Rounds, and K. P. Yip Chest Jul 1998: 35S. [PDF]

Effects of Chronic Hypoxia and Altered Hemodynamics on Endothelial Nitric Oxide Synthase and Preproendothelin-1 Expression in the Adult Rat Lung
Timothy D. Le Cras, Robert C. Tyler, Marilee P. Horan, Ken G. Morris, Ivan F. McMurty, Roger A. Johns, and Steven H. Abman Chest Jul 1998: 35S–36S. [PDF]

Regulation of Pulmonary Endothelial Cell Shape by TRP-Mediated Calcium Entry
Timothy Moore, George Brough, John Kelly, Paul Babal, Ming Li, and Troy Stevens Chest Jul 1998: 36S–38S. [PDF]

Role of Adenylyl Cyclase in Proliferation of Neonatal Pulmonary Artery Smooth Muscle Cells
H. A. Guldemeester, K. R. Stenmark, G. Brough, R. M. Tuder, and T. Stevens Chest Jul 1998: 38S–39S. [PDF]

Increased Pulmonary Blood Flow Alters the Molecular Regulation of Vascular Reactivity in the Lamb
Stephen Black, J. Fineman, M. Johengen, J. Bristow, and S. Soifer Chest Jul 1998: 39S. [PDF]

Hypoxia-inducible Factor 1: From Molecular Biology to Cardiopulmonary Physiology
Gregg L. Semenza, Faton Agani, Narayan Iyer, Bing-Hua Jiang, Sandra Leung, Charles Wiener, and Aimee Yu Chest Jul 1998: 40S–45S. [PDF]

Hypoxia Causes Oxidant Lesions in the Rat Pulmonary Artery Smooth Muscle Cell VEGF Gene: Potential Link to VEGF mRNA Expression
M. N. Gillespie, D. W. Killilea, M. Solomon, P. Babal, S. P. LeDoux, and G. L. Wilson Chest Jul 1998: 45S. [PDF]

Cardiac and Lung VEGF mRNA Expression in Chronically Hypoxic and Monocrotaline-Treated Rats
Chohreh Partovian, A. Ladoux, S. Eddahibi, E. Teiger, B. Raffestin, C. Frelin, and S. Adnot Chest Jul 1998: 45S–46S. [PDF]

Hypoxia-Mediated Modulation of Vascular Function—Implications for Organ Preservation and Thrombogenesis: Roger S. Mitchell Lecture
Shi Fang Yan, Charles A. Lawson, David M. Stern, and David J. Pinsky Chest Jul 1998: 46S–50S. [PDF]

Chemokine Macrophage Inflammatory Protein-1 $agr$ mRNA Expression in Lung Biopsy Specimens of Primary Pulmonary Hypertension
M. Fartoukh, D. Emilie, C. Le Gall, G. Monti, Gerald Simonneau, and Marc Humbert Chest Jul 1998: 50S–51S. [PDF]

Vascular Endothelial Growth Factor Expression Is Decreased in Rat Lung Following Exposure to 24 or 48 Hours of Hyperoxia: Implications for Endothelial Cell Survival
Elizabeth A. Perkett and Jessica G. Klekamp Chest Jul 1998: 52S–53S. [PDF]

Alterations in Nitric Oxide Synthase Isoform Expression in NOS Knockout Mice Exposed to Normoxia or Hypoxia
Timothy R. Quinlan, Victor Laubach, Nan Zhou, and Roger A. Johns Chest Jul 1998: 53S–55S. [PDF]

Relearning the Lessons of History: Anorexigens and Pulmonary Hypertension
David Langleben Chest Jul 1998: 55S–57S. [PDF]

Familial Primary Pulmonary Hypertension Locus Mapped to Chromosome 2q31-q32
Jane H. Morse, A. C. Jones, R. J. Barst, S. E. Hodge, K. C. Wilhelmsen, and T. G. Nygaard Chest Jul 1998: 57S–58S. [PDF]

Mechanisms of Shear Stress Transmission and Transduction in Endothelial Cells
Abdul I. Barakat and Peter F. Davies Chest Jul 1998: 58S–63S. [PDF]

Thrombin Regulation of Endothelin-1 Gene in Isolated Human Pulmonary Endothelial Cells
C. G. Golden, H. S. Nick, and Gary A. Visner Chest Jul 1998: 63S–64S. [PDF]

Endothelial Cell Hypoxic Stress Proteins
Harrision W. Farber and K. K. Graven Chest Jul 1998: 64S–65S. [PDF]

Chronic Intrauterine Pulmonary Hypertension Increases Preproendothelin-1 and Decreases Endothelin B Receptor mRNA Expression in the Ovine Fetal Lung
D. Dunbar Ivy, Timothy D. Le Cras, Marilee P. Horan, and Steven H. Abman Chest Jul 1998: 65S. [PDF]

Influence of Endogenous Endothelial and Neural Nitric Oxide on the Bronchial Vasculature
E. M. Baile and P. D. Paré Chest Jul 1998: 66S. [PDF]

Lung Injury After Heavy Exercise at Altitude
Marlow W. Eldridge, R. K. Braun, K. Y. Yoneda, William F. Walby, S. Bennett, and D. M. Hyde Chest Jul 1998: 66S–67S. [PDF]

MCAF/MCP-1 Protein Expression in a Rat Model for Pulmonary Hypertension Induced by Monocrotaline
Yasunori Kasahara, Hiroshi Kimura, Katsusi Kurosu, Kazutoshi Sugito, Naofumi Mukaida, Kouji Matsushima, and Takayuki Kuriyama Chest Jul 1998: 67S. [PDF]

Pulmonary Endothelial Dysfunction Following Chronic Left Lung Autotransplantation
K. Yoshida, N. Flavahan, Nicholas F. Smedira, and Paul A. Murray Chest Jul 1998: 67S. [PDF]

Vessel-Specific Gene Expression in the Lung: Tissue Plasminogen Activator Expression Is Limited to Bronchial Arteries and Pulmonary Vessels of Discrete Size
Eugene G. Levin, Kent G. Osborn, and Wolf-Dieter Schleuning Chest Jul 1998: 68S. [PDF]

The Ca²⁺-Dependent Isozymes of Protein Kinase C are Uniquely Important in the Enhanced Growth of Immature Adventitial Fibroblasts Isolated From the Bovine Pulmonary Arterial Wall at a Time of Heightened Susceptibility to Vascular Injury
Mita Das, K. R. Stenmark, L. J. Ruff, and Edward C. Dempsey Chest Jul 1998: 68S–69S. [PDF]

Chronic Estradiol Treatment Causes a Marked and Sustained Increase in Pulmonary Blood Flow in the Late Gestation Ovine Fetus
Thomas A. Parker, Henry L. Galan, John P. Kinsella, Gresham Richter, Marilee P. Horan, and Steven H. Abman Chest Jul 1998: 69S. [PDF]

Effect of Dimethyl Amiloride on Chronic Hypoxic Pulmonary Hypertension in Rats
Deborah Quinn, H. K. Du, B. T. Thompson, H. G. Garg, and C. A. Hales Chest Jul 1998: 69S–70S. [PDF]

The Effect of Inhaled Nitric Oxide on 6-Minute Walk Distance in Patients With Pulmonary Hypertension
S. Parsons, D. Celermajer, E. Savidis, O. Miller, and I. Young Chest Jul 1998: 70S–72S. [PDF]

Endothelial Dysfunction Providing the Basis for the Treatment of Pulmonary Hypertension: Giles F. Filley Lecture
Timothy W. Higenbottam and Elizabeth A. Laude Chest Jul 1998: 72S–79S. [PDF]

Exaggerated Pulmonary Hypertensive Responses During Chronic Hypoxia in Mice With Gene-Targeted Reductions in Atrial Natriuretic Peptide
James R. Klinger, R. R. Warburton, L. A. Pietras, R. Swift, S. John, and N. S. Hill Chest Jul 1998: 79S–80S. [PDF]

Treatment of Severe Pulmonary Hypertension Secondary to Connective Tissue Diseases With Continuous IV Epoprostenol (Prostacyclin)
M. Humbert, O. Sanchez, M. Fartoukh, J-L. Jagot, O. Sitbon, and G. Simonneau Chest Jul 1998: 80S–82S. [PDF]

Smooth Muscle Cell Heterogeneity: Role of Specific Smooth Muscle Cell Subpopulations in Pulmonary Vascular Disease
Kurt R. Stenmark and Maria G. Frid Chest Jul 1998: 82S–90S. [PDF]

Angiotensin II Stimulates Proliferation of Human Pulmonary Artery Smooth Muscle Cells via the AT1 Receptor
Nicholas W. Morrell, P. D. Upton, M. A. Higham, Magdi H. Yacoub, J. M. Polak, and J. Wharton Chest Jul 1998: 90S–91S. [PDF]

A Novel Orally Active Endothelin-A Receptor Antagonist, ZD1611, Prevents Chronic Hypoxia-Induced Pulmonary Hypertension in the Rat
Russell A. Bialecki, C. Stinson-Fisher, W. Murdoch, D. Bertelsen, M. Desiato, and W. Rumsey Chest Jul 1998: 91S. [PDF]

Vascular Remodeling—The Emerging Paradigm of Programmed Cell Death (Apoptosis): The Francis B. Parker Lectureship
Victor J. Dzau and Masatsugu Horiuchi Chest Jul 1998: 91S–99S. [PDF]

Pulmonary Prostacyclin Synthase Overexpression by Adenovirus Transfection and in Transgenic Mice
Mark Geraci, Bifeng Gao, David Shepherd, Jerry Allard, David Curiel, Jay Westcott, and Norbert Voelkel Chest Jul 1998: 99S. [PDF]

High-Frequency Oscillatory Ventilation Augments the Response to Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn
John P. Kinsella, Steven H. Abman Nitric Oxide Study Group Chest Jul 1998: 100S. [PDF]

Effect of Nitric Oxide on Transgene Expression in Vascular Smooth Muscle Cells
Karen Fagan, Lisa K. Hepler, Ivan F. McMurtry, and David M. Rodman Chest Jul 1998: 100S–101S. [PDF]

The Pressure-Overloaded Right Ventricle in Pulmonary Hypertension
Michael R. Bristow, Lawrence S. Zisman, Brian D. Lowes, William T. Abraham, David B. Badesch, Bertron M. Groves, Norbert F. Voelkel, David M.B. Lynch, and Robert A. Quaife Chest Jul 1998: 101S–106S. [PDF]

Conference Summary: Biology & Pathobiology of the Lung Circulation
Robert P. Mecham Chest Jul 1998: 106S–111S. [PDF]