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University of Colorado Health Science Center Denver, CO
Correspondence to: Edward Abraham, MD, FCCP, Pulmonary Science, Critical Care, Univ Colorado Health Science Center, 4200 E Ninth Ave, Denver, CO 80262
Acute lung injury was the focus of the 41st Annual Thomas L. Petty Aspen Lung Conference. ARDS and acute lung injury had also been the topic 5 years previously and initially, in organizing the conference, we were concerned that there was not sufficient evolution in the field to justify a return to the same subject within such a short interval. Our concerns were rapidly laid to rest as we generated our first list of topics that we hoped could be covered. Our enthusiasm for a review of advances in acute lung injury grew as the conference took form. We believe that our enthusiasm for the topics covered was shared by the participants in the meeting and will be shared by readers of the summaries of the presentations.
We were extremely fortunate to have Tom Petty, MD, Master FCCP, as the initial speaker for the conference. He provided an enlightening historical perspective of ARDS that served as an outstanding introduction for the state-of-the-art and scientific presentations. The Aspen setting provides ample opportunity for interaction between speakers and the audience. This conference was not an exception to this, and discussions concerning mechanisms and manifestations of acute lung injury started at breakfast and continued into the evening. Michael Matthay, MD, FCCP, who provided an outstanding summary of the meeting, was able to achieve the seemingly impossible task of providing a context for the rich scientific material presented.
We are deeply indebted to all of the conference participants who helped make this meeting a success. The conference was centered on the intracellular and extracellular signaling mechanisms leading to inflammatory injury in the lungs. We came away with an enhanced appreciation of the multiplicity of pathways that can lead to lung injury. The future challenge will be in developing useful therapies for patients with ARDS and acute lung injury based on our increased understanding of the mechanisms leading to these clinical entities.
Jeanne Cleary deserves special recognition for her contribution to the conference organization. She was able to keep us to a time schedule in developing the conference and attended to the myriad of details, including hotels and catering, required for the success of the meeting. We would like to thank Marvin Schwarz, MD, FCCP, for his continuing devotion to the Aspen conference series. Mike Baird and Wayne Silvers again provided essential background help. As always, the conference would not have been possible without the continued support of the Francis Families Foundation and the many representatives of the pharmaceutical industry.
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