Thrombocytopenia--a rare but potentially serious side effect of initial daily and interrupted use of rifampicin.

  1. C H Lee and
  2. C J Lee
  1. Department of Chest Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.

Abstract

Thrombocytopenia is occasionally caused by rifampicin, when high-doses are given twice-weekly. This complication is rare when the medication is given in small daily doses, or following a prolonged interruption of therapy. Two cases of rifampicin-induced thrombocytopenia are reported. One occurred within four days of the initiation of small daily doses and the other following a prolonged interruption of therapy.

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