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Chest, Vol 81, 707-710, Copyright © 1982 by American College of Chest Physicians

ARTICLES

Ventilatory response to isocapnic hypoxia in parents of victims of sudden infant death syndrome

PL Schiffman, C Remolina, RE Westlake, TV Santiago and NH Edelman

Ventilatory response to progressive isocapnic hypoxia was measured in 14 parents of victims of sudden infant death syndrome (SIDS) and 12 matched control parents. Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 +/- 46.4, while SIDS parents had a significantly lower value of 64.4 +/- 16.2 (P less than 0.01). Since degree of hypoxic ventilatory drive is a hereditary characteristic, it is concluded that a relatively low ventilatory responsiveness to hypoxia might have been present in the SIDS victims.


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Copyright © 1982 by the American College of Chest Physicians.