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Chest, Vol 79, 647-650, Copyright © 1981 by American College of Chest Physicians

ARTICLES

Prevention of pulmonary emboli in a respiratory intensive care unit: efficacy of low-dose heparin

SK Pingleton, RC Bone, WW Pingleton and WE Ruth

Ninety-eight patients admitted to our respiratory intensive care unit during a one-year period were compared retrospectively with 99 well- matched patients admitted during a second one-year period. The use of prophylactic low-dose heparin in the second year was associated with a significant decrease in pulmonary emboli documented by ventilation- perfusion scan, pulmonary angiography, and autopsy. No specific bleeding complications could be directly attributed to the use of low- dose heparin. The frequency and severity of gastrointestinal hemorrhage as determined by hemoglobin fall and transfusion requirements were not significantly affected by the prophylactic use of low-dose heparin. Low- dose heparin appears to be effective and safe in respiratory intensive care unit patients in the prevention of pulmonary emboli.


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W. Geerts and R. Selby
Prevention of Venous Thromboembolism in the ICU
Chest, December 1, 2003; 124(6_suppl): 357S - 363S.
[Abstract] [Full Text] [PDF]


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Copyright © 1981 by the American College of Chest Physicians.