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Chest, Vol 79, 416-419, Copyright © 1981 by American College of Chest Physicians

ARTICLES

Salbutamol inhalation in chronic asthma bronchiale: dose aerosol vs jet nebulizer

P Christensson, M Arborelius Jr and B Lilja

The effect of inhalation of 5 mg of salbutamol by a jet nebulizer and 0.3 mg from a metered aerosol was compared in 20 patients with chronic asthma. Half the patients, randomly selected, received one treatment method on day one and the other on day two. A battery of lung function tests suitable for detecting large and small airways obstruction showed only insignificantly more pronounced bronchodilatation after the use of the jet nebulizer. Neither was a better dilation of small airways with this method obvious. It is concluded that the higher dose by jet- nebulizer is only clinically motivated when the patients cannot perform the deep inhalations and breathholding necessary for efficient use of the dose aerosol.


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 Qual Saf Health CareHome page
J Wright, D Brocklebank, and F Ram
Inhaler devices for the treatment of asthma and chronic obstructive airways disease (COPD)
Qual. Saf. Health Care, January 12, 2002; 11(4): 376 - 382.
[Abstract] [Full Text] [PDF]


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Copyright © 1981 by the American College of Chest Physicians.