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Chest, Vol 79, 102-104, Copyright © 1981 by American College of Chest Physicians

ARTICLES

Angiotensin-converting enzyme in farmer's lung

DA Tewksbury, JJ Marx Jr, RC Roberts and DA Emanuel

Serum levels of angiotensin-converting enzyme were measured in a group of patients with farmer's lung and a group of precipitin-positive subjects with no history of farmer's lung. The levels did not differ significantly from control subjects matched for age and smoking history. The mean serum level of angiotensin-converting enzyme in a group of acutely ill patients with farmer's lung was significantly reduced. An acute challenge of three patients with Micropolyspora faeni did not produce an increase in serum levels of angiotensin-converting enzyme. These studies suggest that an increased serum level of angiotensin-converting enzyme can be a diagnostic aid in making a differential diagnosis between sarcoidosis and farmer's lung.




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Copyright © 1981 by the American College of Chest Physicians.