Chest
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kearley, R
Right arrow Articles by Martin, C
Right arrow Search for Related Content
PubMed
Right arrow Articles by Kearley, R
Right arrow Articles by Martin, C

Chest, Vol 78, 682-685, Copyright © 1980 by American College of Chest Physicians

ARTICLES

The effect of low flow oxygen on sleep-disordered breathing and oxygen desaturation. A study of patients with chronic obstructive lung disease

R Kearley, JW Wynne, AJ Block, PG Boysen, S Lindsey and C Martin

Oxygen desaturation occurs during sleep in many patients with chronic obstructive lung disease (COLD) and is often caused by sleep-disordered breathing (SDB). Nocturnal oxygen therapy should improve nighttime hypoxemia, but might also worsen SDB. Using standard polysomnographic techniques, we evaluated the frequency and duration of oxygen desaturation and SDB during sleep in 11 patients with stable COLD. During half of the night the patients breathed air through a nasal cannula and during the other half of the night they breathed oxygen at 2 liters per minute. Five patients had arterial lines inserted for determination of arterial blood gas levels during periods of SDB or desaturation. The ten men and one woman slept 70 minutes (52 percent of time in bed) while on air and 111 minutes (80 percent of time in bed) while on oxygen (p < 0.001). Oxygen therapy reduced the number of episodes of desaturation per hour and the time spent in desaturation. However, there was no difference between air and oxygen in episodes of SDB per hour, the duration of episodes of SDB, baseline sleeping PaCO2 or PaCO2 during episodes of desaturation or SDB. Therefore, in most patients with stable COLD, administration of oxygen at 2 liters per minute improves oxygenation, prolongs sleep, but does not adversely affect SDB.


This article has been cited by other articles:


Home page
 Arch. Dis. Child.Home page
M P Villa, J Pagani, V Lucidi, S Palamides, and R Ronchetti
Nocturnal oximetry in infants with cystic fibrosis
Arch. Dis. Child., January 1, 2001; 84(1): 50 - 54.
[Abstract] [Full Text]

Home page
 ChestHome page
R. J. Martin, B. L. Bucher Bartelson, P. Smith, D. W. Hudgel, D. Lewis, G. Pohl, P. Koker, and J. F. Souhrada
Effect of Ipratropium Bromide Treatment on Oxygen Saturation and Sleep Quality in COPD
Chest, May 1, 1999; 115(5): 1338 - 1345.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1980 by the American College of Chest Physicians.