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Chest, Vol 78, 264-268, Copyright © 1980 by American College of Chest Physicians

ARTICLES

Familial spontaneous pneumothorax and HLA antigens

IK Sharpe, M Ahmad and W Braun

Twenty-three members of a family in which six persons had repeated spontaneous pneumothorces were studied for physical, chemical and genetic markers of this disease. A relationship between the HLA haplotype A2, B40, the alpha 1, antitrypsin phenotype M1 M2 and the occurrence of spontaneous pneumothorax was suggested in this family.


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