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Chest, Vol 77, 800-801, Copyright © 1980 by American College of Chest Physicians

ARTICLES

Interaction of rifampin and chlorpropamide

TH Self and T Morris

A 62-year-old man who had been taking 250 mg of chlorpropamide daily for several years received rifampin concomitantly and had a subsequent increased dosing requirement of chlorpropamide. When rifampin was discontinued several months later, the serum chlorpropamide concentration rose dramatically.


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