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Chest, Vol 77, 572-574, Copyright © 1980 by American College of Chest Physicians

ARTICLES

Estimated and determined P50 values in erythrocytosis

BA Neilan, P Gunter, AB Adams and PB Johnson

Actual determination of the position of the oxygen-hemoglobin dissociation curve (P50) was compared to three methods of estimating P50 in 20 patients with erythrocytosis. There was a significant correlation between determined and estimated P50 values for each of the methods studied. Furthermore, four patients with high affinity hemoglobins were readily distinguished from the other patients by estimating P50. The data suggest that calculating P50 is reliable and may replace the need for actual measurement.




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Copyright © 1980 by the American College of Chest Physicians.