Chest ACCP Career Connection
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Roethe, R.
Right arrow Articles by Hafermann, D.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Roethe, R.
Right arrow Articles by Hafermann, D.

Chest, Vol 77, 400-402, Copyright © 1980 by American College of Chest Physicians

ARTICLES

Transbronchoscopic lung biopsy in sarcoidosis. Optimal number and sites for diagnosis

RA Roethe, PB Fuller, RB Byrd and DR Hafermann

By obtaining five transbronchoscopic biopsies of the lung from each of the right upper and lower lobes, the diagnosis of sarcoidosis was made in 36 of 37 prospectively studied patients. The diagnosis was made in all ten patients with stage-1 disease, but seven of the ten showed diagnostic tissue from only one lobe. Only one of the ten biopsies was diagnostic in four of those patients with a stage-1 disease. In disease of stage 2 and 3, there was good correlation between diagnostic biopsies and the radiographic distribution of infiltrates. Biopsies from the predominantly rather than the lesser involved lobe proved the diagnosis in all of these patients, except for the two patients with nodular sarcoid. We conclude that ten biopsies are optimal for obtaining the diagnosis in stage-1 disease; however, five biopsies may be adequate in non-nodular disease of stage 2 and 3 if the biopsies are of the lobe predominantly involved on the roentgenogram of the chest.


This article has been cited by other articles:


Home page
 ChestHome page
F. Girvin and I. Vlahos
A 30-year-old man with a history of polysubstance abuse and hepatitis C presents with exertional dyspnea and patchy ground-glass opacities.
Chest, November 1, 2006; 130(5): 1608 - 1611.
[Full Text] [PDF]

Home page
 Eur Respir JHome page
J. T. Annema, M. Veselic, and K. F. Rabe
Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of sarcoidosis
Eur. Respir. J., March 1, 2005; 25(3): 405 - 409.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
L. S. Newman, M. M. Mroz, R. Balkissoon, and L. A. Maier
Beryllium Sensitization Progresses to Chronic Beryllium Disease: A Longitudinal Study of Disease Risk
Am. J. Respir. Crit. Care Med., January 1, 2005; 171(1): 54 - 60.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
T. Takahashi, A. Azuma, S. Abe, O. Kawanami, K. Ohara, and S. Kudoh
Significance of lymphocytosis in bronchoalveolar lavage in suspected ocular sarcoidosis
Eur. Respir. J., September 1, 2001; 18(3): 515 - 521.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
G. Hunninghake
Statement on Sarcoidosis
Am. J. Respir. Crit. Care Med., August 1, 1999; 160(2): 736 - 755.
[Full Text]

Home page
 NEJMHome page
H. W. Querfurth and E. J. Mark
Case 8-1998- A 41-Year-Old Man with Leg Weakness and Mediastinal Lymphadenopathy
N. Engl. J. Med., March 12, 1998; 338(11): 747 - 754.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1980 by the American College of Chest Physicians.