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Chest, Vol 77, 227-230, Copyright © 1980 by American College of Chest Physicians

ARTICLES

Pentazocine abuse. Report of a case with pulmonary arterial cellulose granulomas and pulmonary hypertension

RJ Houck, GL Bailey, PJ Daroca Jr, F Brazda, FB Johnson and RC Klein

We report a patient who developed pulmonary hypertension following repeated intravenous injection of dissolved pentazocine tablets. Through analysis of lung biopsy material, this was shown to be due to embolization of the cellulose filler in the tablet and the tissue reaction it produced. Administration of prednisone appeared to improve the patient's clinical state.




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Copyright © 1980 by the American College of Chest Physicians.