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Chest, Vol 74, 671-672, Copyright © 1978 by American College of Chest Physicians

ARTICLES

Superior vena cava syndrome caused by invasive aspergillosis

G Gartenberg, K Einstein and J Jagirdar

A 37-year-old man with blastic crisis of chronic myelogenous leukemia was admitted for chemotherapy. After treatment with an infusion of vincristine, he became leukopenic and febrile. Two episodes of gram- negative septicemia were treated with prolonged courses of antibiotics; however, fever persisted, and the patient developed the superior vena cava syndrome. Despite therapy with amphotericin B, the patient died. At autopsy a thrombus of Aspergillus was found completely occluding the superior vena cava.




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Copyright © 1978 by the American College of Chest Physicians.