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Chest, Vol 69, 117-119, Copyright © 1976 by American College of Chest Physicians

ARTICLES

Acute cardiomyopathy with recurrent pulmonary edema and hypotension following heroin overdosage

SK Paranthaman and F Khan

An 18-year-old man developed acute pulmonary edema following heroin overdose. Two days after initial improvement, there was recurrence of hypotension and pulmonary edema with severe hypoxemia refractory to mechanical ventilatory support utilizing positive and end-expiratory pressure. Cardiac catheterization revealed elevated pulmonary capillary wedge pressure suggestive of left ventricular failure. The use of digitalis and diuretics resulted in prompt clinical improvement and ultimate recovery. Evidence is presented indicating that this patient represents an uncommon but important syndrome of acute cardiomyopathy with left ventricular failure which complicates the clinical course of certain cases of heroin overdose. Its physiologic diagnosis is of obvious importance in the choice of proper therapy, thereby increasing the patient's chances of recovery.


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 ChestHome page
K. A. Sporer and E. Dorn
Heroin-Related Noncardiogenic Pulmonary Edema : A Case Series
Chest, November 1, 2001; 120(5): 1628 - 1632.
[Abstract] [Full Text] [PDF]

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 ANN INTERN MEDHome page
K. A. Sporer
Acute Heroin Overdose
Ann Intern Med, April 6, 1999; 130(7): 584 - 590.
[Abstract] [Full Text] [PDF]


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Copyright © 1976 by the American College of Chest Physicians.