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Chest, Vol 69, 112-113, Copyright © 1976 by American College of Chest Physicians

ARTICLES

Acute respiratory failure precipitated by a carbonic anhydrase inhibitor

WL Coudon and AJ Block

A 60-year-old white man with chronic bronchitis was noted to develop acute respiratory failure and metabolic acidosis four days after being started on methazolamide (Neptazane) for an ophthalmologic problem. The patient was intubated with ventilator support and improved after his metabolic acidosis resolved. Caution is emphasized in the use of carbonic anhydrase inhibitors in patients with obstructive airway disease.


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A. M. Luks and E. R. Swenson
Medication and Dosage Considerations in the Prophylaxis and Treatment of High-Altitude Illness
Chest, March 1, 2008; 133(3): 744 - 755.
[Abstract] [Full Text] [PDF]


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Copyright © 1976 by the American College of Chest Physicians.