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(Chest. 1973;64:256-259.)
© 1973 American College of Chest Physicians

Cold Injury and Clubbing: A Possible relationship

Vijay Soman M.D.1 and Melvin Hershkowitz M.D.2

1 Chief Resident, Department of Medicine
2 Associate Director, Department of Medicine

A 40-year-old Negro truck driver with pneumonia showed advanced clubbing of the fingers and toes, unrelated to his acute infection. No reliable hereditary basis could be documented. The chronology of the observed changes suggested that an episode of exposure to severe cold in Korea at age 21 might have been the crucial initiating factor in the development of his clubbing. Rabbits exposed to severe cold develop productive bone changes, and a possible unidentified mechanism could produce similar changes in man. However, the rarity of this response to cold injury remains unexplained in man.






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Copyright © 1973 by the American College of Chest Physicians.