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(Chest. 1973;64:246-248.)
© 1973 American College of Chest Physicians

Pleural Effusion Due to Multiple Myeloma

Ali M. Safa M.D.1 and H. S. Van Ordstrand M.D., F.C.C.P.2

1 Department of Pulmonary Disease and the Division of Medicine. The Cleveland Clinic Foundation and The Cleveland Clinic Educational Foundation Cleveland, Ohio
2 Head, Department of Pulmonary Disease, The Cleveland Clinic Foundation

A case of multiple myeloma with massive pleural involvement is reported. The diagnosis was made by the finding of high protein content, high specific gravity, and many plasma cells in the pleural fluid. The diagnosis was further confirmed on examination of the pleural biopsy specimen (by Cope needle). Protein electrophoresis of pleural fluid revealed a sharp-spiked peak in gamma globulin.




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