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(Chest. 1973;63:1023-1025.)
© 1973 American College of Chest Physicians

Hyperkalemic Cardiac Arrhythmia Secondary to Spironolactone

Chalat Pongpaew M.D.1; Revadee Na Songkhla M.D.1; and Robert L. Kozam M.D.1

1 Division of Cardiology, Methodist Hospital of Brooklyn, Brooklyn

Although multiple adverse reactions can occur during the use of spironolactone, the most serious complication is related to its potassium-sparing effect which may induce dangerous and even fatal hyperkalemia. One patient is presented who developed severe hyperkalemia after spironolactone resulting in ventricular standstill and survival following treatment with sodium bicarbonate.






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Copyright © 1973 by the American College of Chest Physicians.