Chest ACCP Member Benefits
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Scott, E. G.
Right arrow Articles by Hunt, W. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Scott, E. G.
Right arrow Articles by Hunt, W. B., Jr.
(Chest. 1973;63:701-706.)
© 1973 American College of Chest Physicians

Silo Filler's Disease

Ewell G. Scott M.D.1 and W. B. Hunt Jr. M.D.1

1 Associate Professor of Medicine, University of Virginia School of Medicine, Charlottesville, Va.

There are few longitudinal studies of lung function following exposure of man to silage gas. Four episodes of silo filler's disease (nitrogen dioxide poisoning) in three patients are described, with serial pulmonary function studies. Obstructive, restrictive and diffusion defects were observedacutely, with almost complete clearing of detectable disease within the observation period (327, 10, 75, and 28 days). An analysis of the information concerning chronic pulmonary disease and nitrogen dioxide exposure leads the authors to conclude: 1) silo filler's disease may occasionally lead to chronic pulmonary disease by (a) the survival of the patient, despite severe bronchiolar injury by the nitrogen dioxide or more commonly, (b) less severe residual bronchiolar injury after exposure in patients with pre-existing "small airway disease" (chronic bronchitis and emphysema predominantly); 2) animal exposure studies and lung biopsies in human beings lead to the speculation that the chronic disease which is produced may be centrulogbar emphysema.




This article has been cited by other articles:


Home page
 Am. J. Respir. Crit. Care Med.Home page
M. Schenker
Respiratory Health Hazards in Agriculture
Am. J. Respir. Crit. Care Med., November 1, 1998; 158(2007): S1 - S76.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1973 by the American College of Chest Physicians.