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(Chest. 1996;110:284S-294S.)
© 1996 American College of Chest Physicians

Lung Transplantation for agr1-Antitrypsin Deficiency Emphysema

E. P. Trulock MD, FCCP1

1 From the Lung Transplant Program, Washington University-Barnes Hospital, St. Louis

Lung transplantation is an option for appropriately selected patients with end-stage emphysema caused by agr1-antitrypsin deficiency. The functional results have been excellent after single or bilateral lung transplantation, and the medium-term survival results have been good. However, the role of agr1-antitrypsin replacement therapy after lung transplantation remains uncertain, and further investigation is needed.

Key Words: antitrypsin deficiency • chronic obstructive pulmonary disease • lung transplantation






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