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(Chest. 1996;110:273S-277S.)
© 1996 American College of Chest Physicians

The Interdependence of Lung Antioxidants and Antiprotease Defense in ARDS

James E. Gadek MD, FCCP1 and Eric R. Pacht MD1

1 From the Department of Internal Medicine, Ohio State University, Columbus

As in hereditary agr1-antitrypsin deficiency, protease-antiprotease and oxidant-antioxidant balances play a significant role in the pathogenesis of ARDS. However, the disease processes and possibilities for therapeutic intervention differ markedly.

Key Words: adult respiratory distress syndrome • antioxidant • antiprotease • agr1-antitrypsin • neutrophil elastase • oxidant • protease • surfactant






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Copyright © 1996 by the American College of Chest Physicians.